Tacrolimus-Associated Dilated Cardiomyopathy in Adult Patient After Orthotopic Liver Transplant

نویسندگان

  • Jennifer McLeod
  • Stephanie Wu
  • Luanda Grazette
  • Anna Sarcon
چکیده

This report presents a case of tacrolimus cardiotoxicity in an adult patient who received tacrolimus immunosuppression for orthotopic liver transplant (OLT). Tacrolimus-associated cardiotoxicity has been described in the literature, however this is the first case to document the development of a dilated cardiomyopathy in a patient shortly after initiating tacrolimus therapy post transplant. With the growing use of tacrolimus in transplant medicine, this case report expands the literature of tacrolimus cardiotoxicity and can aid clinicians in the evaluation and management of patients exposed to this form of immunosuppression.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Broken Heart Syndrome (Takotsubo Cardiomyopathy) Triggered by Orthotopic Liver Transplantation

Upon extensive review of literature, Takotsubo cardiomyopathy post orthotopic liver transplant has been reported in only few cases. Herein we present a case of Takotsubo cardiomyopathy post orthotopic liver transplantation. In our case, we aim to illustrate the importance of early recognition of this condition since stress induced cardiomyopathy is an underestimated cause of cardiac complicatio...

متن کامل

Clinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients

Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...

متن کامل

Clinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients

Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...

متن کامل

Postoperative left ventricular apical ballooning: Transient Takotsubo cardiomyopathy following orthotopic liver transplantation

PATIENT Female, 51 FINAL DIAGNOSIS: Takotsubo cardiomyopathy Symptoms: - MEDICATION - Clinical Procedure: - Specialty: Cardiology • Transplantology. OBJECTIVE Rare disease. BACKGROUND Left ventricular apical ballooning syndrome (LVAB), also known as Takotsubo cardiomyopathy, is a cardiac syndrome characterized by transient left ventricular dysfunction in the absence of obstructive atheros...

متن کامل

A rare but important adverse effect of tacrolimus in a heart transplant recipient: diabetic ketoacidosis.

Heart transplantation indications in pediatric population include congenital heart diseases, cardiomyopathies and retransplants. Cardiomyopathy is the primary indication for 11 to 17 years of age. The surveillance after transplantation is a very important issue because of both the rejection risk and the adverse effects due to medications after transplantation. Immunosuppressive agents that are ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2017